Global Opioid Induced Constipation Market size and share is currently valued at USD 3.93 billion in 2024 and is anticipated to generate an estimated revenue of USD 3.93 billion by 2032, according to the latest study by Polaris Market Research. Besides, the report notes that the market exhibits a robust 4.6% Compound Annual Growth Rate (CAGR) over the forecasted timeframe, 2024 - 2032

Market Overview

Opioid-induced constipation is a prevalent side effect of opioid analgesics, which are commonly prescribed for managing chronic pain. The condition arises when opioids bind to receptors in the gastrointestinal tract, leading to reduced motility and resultant constipation. As the global population ages and the incidence of chronic pain increases, the demand for effective OIC treatments has surged. This trend is further amplified by the opioid epidemic, which has heightened awareness and the need for specialized therapies. ​

Market Segmentation

By Prescription Type

• Prescription Medications: Dominating the market, prescription drugs offer targeted relief for OIC symptoms and are often preferred due to their efficacy. ​

• Over-the-Counter (OTC) Medications: While OTC options are available, they are typically used for mild cases or as adjuncts to prescription therapies.​

By Drug Class

• Mu-Opioid Receptor Antagonists: This class includes medications like naloxegol (Movantik), naldemedine (Symproic), and alvimopan (Entereg), which specifically target opioid receptors in the gut to alleviate constipation without affecting pain relief. ​

• Chloride Channel Activators: Lubiprostone (Amitiza) is a prominent drug in this category, enhancing fluid secretion in the intestines to facilitate bowel movements. ​

By Distribution Channel

• Hospitals: Serving as primary centers for OIC management, hospitals account for a significant share of the market due to the high volume of opioid prescriptions and the need for specialized care. 

• Retail Pharmacies: These outlets provide accessibility to OTC OIC treatments and support adherence to prescribed therapies.​

• Online Pharmacies: The growing trend of e-commerce has facilitated the rise of online pharmacies, offering convenience and privacy for patients seeking OIC medications.​

Regional Analysis

North America

Leading the global market, North America holds a dominant share, driven by high opioid prescription rates and a well-established healthcare infrastructure. The United States, in particular, has witnessed a significant increase in OIC prescriptions, with over 142 million recorded in 2020 alone. ​

Europe

Europe exhibits steady growth in the OIC market, supported by favorable healthcare policies and ongoing research initiatives aimed at improving pain management and patient outcomes. The region's focus on patient-centric care and the integration of digital health solutions are also contributing to market growth. ​

Asia-Pacific

Anticipated to witness the highest growth rate, the Asia-Pacific region is experiencing rapid advancements in healthcare infrastructure, increased awareness about OIC, and a burgeoning middle-class population. Countries like China, India, and Japan are at the forefront of this growth, with significant investments in healthcare and pain management practices. ​

Key Companies

• Aurobindo Pharma (India)
• Bayer AG (Germany)
• Boehringer Ingelheim International GmbH. (Germany)
• Bristol Myers Squibb Company (US)
• Cosmo Pharmaceuticals (Ireland)
• Daewoong Pharmaceutical Company (South Korea)
• F. Hoffmann-La Roche Ltd (Switzerland)
• Fresenius Kabi AG (Germany)
• GSK Plc. (UK)
• Hikma Pharmaceuticals PLC (UK)
• Merck & Co Inc. (US)
• Mylan NV (US)

Explore More:

https://www.polarismarketresearch.com/industry-analysis/opioid-induced-constipation-market 

Conclusion

The opioid-induced constipation market is poised for continued growth, driven by the increasing prevalence of chronic pain, the widespread use of opioid analgesics, and the rising demand for effective treatments. With advancements in pharmaceutical research and a focus on patient-centric care, the market is expected to expand, offering improved therapeutic options for individuals affected by OIC globally.

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