Chronic Venous Insufficiency (CVI) is a long-lasting condition that is characterized by inadequate blood flow in the veins of the lower legs. This condition occurs due to weakened or damaged vein valves or vein walls, leading to the accumulation of blood in the legs. The result is a variety of symptoms, including swelling, varicose veins, skin discoloration, and, in severe cases, leg ulcers. Risk factors for CVI include extended periods of sitting or standing, obesity, aging, pregnancy, and a genetic tendency toward venous disorders. The severity of symptoms can vary, but common issues include leg heaviness, cramping, pain, and swelling. Early detection and prompt treatment are essential for slowing disease progression and improving the patient’s quality of life.

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CVI Epidemiological Segmentation (2020–2034) – 7MM

• Overall Prevalence of CVI
  
  

• Prevalence by Gender
  
  

• Prevalence by Age Group
  
  

• Number of Treatable Cases
  
  

CVI Epidemiology (2023 Snapshot)

As of 2023, Chronic Venous Disease (CVD), which encompasses CVI, impacted approximately 463 million people across the seven major markets (7MM).

In the United States, there were about 6.2 million reported cases of CVI.

The C1 stage of CVI was the most frequently diagnosed form of the disease in the US.

Epidemiological data indicates that CVI is more prevalent in females and older adults, which is consistent with the disease’s progressive nature.

CVI Market Overview

The market for CVI therapies and devices in the 7MM was valued at around USD 2 billion in 2023.

Market Growth Drivers:

• Increased awareness of CVI and its related health concerns is driving the use of advanced diagnostic tools and treatment options.
  
  

• Technological advancements, particularly in minimally invasive treatments like endovenous procedures and next-generation devices, are transforming the way CVI is treated.
  
  

Market Challenges:

• The high costs associated with advanced treatments and devices may limit access, particularly in healthcare systems with constrained budgets.
  
  

• Patient adherence to lifestyle changes and the consistent use of compression therapy remains a significant challenge in effectively managing CVI.

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Emerging CVI Treatment Devices

• VenoValve
  
  

• EnVVe
  
  

• SONOVEIN
  
  

• Other devices in development
  
  

Key Industry Players in the CVI Space

• Philips
  
  

• BD (Becton, Dickinson and Company)
  
  

• Medtronic
  
  

• Tactile Medical
  
  

• Koya Medical
  
  

• Verigraft AB
  
  

• enVVeno Medical Corporation
  
  

• Theraclion
  
  

• And others

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